New Technology of Adsorption Separation-Examples of Adsorption in Organic Solvents

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Adsorption resins are generally used to adsorb hydrophobic organic substances from an aqueous solution, and the organic substances adsorbed on the resin are eluted with a polar organic solvent or an aqueous solution of a certain concentration. The emergence of some new adsorption resins has made the adsorption of fat-soluble or water-insoluble substances from organic systems successful, greatly expanding the application range of adsorption resins. Examples are as follows:

1. Adsorption of plant pigments.

Saponins can be extracted with water, but a large amount of pigments are often adsorbed and eluted together with the saponins, making the extract darker in color. D280 and D268 can adsorb pigments from ethanol solution, and saponins flow out of the resin column with the ethanol solution to realize the separation of saponins and pigments. ADS-7 can adsorb saponins and pigments at the same time, but the separation of the two can be achieved by step-by-step elution.

  1. Purification of flavonoids.

ADS-11 can adsorb flavonoids from organic solvents by a complexing mechanism, which can purify ginkgo leaf extract (flavonoid content 24-30%) and sea buckthorn extract (flavonoid content 14.9%) to 54.7% and 55.7%, respectively.

Before purification
After purification
  1. Adsorption of alkaloids

Vinblastine includes many components such as vinblastine, vinblastine and ventolin. ADS-13 can not only adsorb these components from chloroform, but also separate some components through stepwise elution.

Vinblastine component adsorbed by ADS-13

  1. Separation of Gardenia Yellow and Geniposide

Adsorb gardenia yellow from a 30% ethanol solution, and the eluate is shown on the left. The color price is 55. The eluate obtained by eluting with 30% ethanol is shown on the right, and the color value reaches 170.